LVV
Lentiviral vectors
Vector genome measurements, functional-titer strategy and cellular VCN, with the distinction between each made explicit.
Explore LVV analyticsMolecular analytical development
Analytical confidence.
For next-generation
therapies.
Independent scientific consulting for cell and gene therapy. Modality-informed analytical strategies for LVV, AAV and targeted LNP/RNA—from the first question to a defensible next step.
Modality-informed strategyMolecular assay designEvidence-led interpretation
01 / Therapeutic modalities
Different systems.
Different analytical questions.
Start with the product. Build an analytical strategy around its biology, quality attributes and development decisions.
AAV
Adeno-associated viral vectors
Genome titer and sequence characterization, connected to capsid attributes and product-specific biological function.
Explore AAV analytics
tLNP / RNA
Targeted LNP & RNA therapeutics
RNA payload quality, formulation attributes and the evidence needed to assess productive target-cell delivery.
Explore tLNP / RNA analyticsConceptual scientific illustrations retained from the original Genometrion website. They are not to scale and do not represent experimentally validated molecular structures.
02 / Molecular methods
The question comes first.
The technology follows.
NGS, digital PCR and quantitative PCR are most useful when the readout, controls and interpretation are defined together.
Sequence-resolved characterization
Study design and interpretation for genome identity, heterogeneity and relevant integration questions.
- Library and platform strategy
- Bioinformatics requirements
- Controls and evidence limits
Digital PCR & ddPCR
Target quantification with explicit units, normalization, partition-quality assessment and matrix controls.
- Genome titer and cellular VCN
- Residual nucleic-acid targets
- Precision and uncertainty
qPCR & RT-qPCR
Quantitative assay design that connects target specificity, calibration and RNA conversion to the result.
- DNA and RNA workflows
- Reference and inhibition controls
- Performance study planning
03 / Analytical development
From critical attribute
to a practical evidence plan.
A structured engagement connects the measurement to its intended use, then makes the next step clear.
Define the decision
Product, stage, sample, quality attribute and the question the result needs to answer.
Review the evidence
Method suitability, controls, uncertainty and the gaps in the current data.
Plan the study
Assay architecture, performance criteria and complementary measurements.
Make it actionable
A documented roadmap, technical assessment or transfer-readiness package.
04 / Tangible consulting outputs
Scientific clarity.
Something you can work with.
Every scope starts with an agreed question and a defined deliverable. The focus is useful analytical reasoning that your team can review and put into practice.
Explore development consulting01
An analytical roadmap
Prioritized attributes, methods, controls and evidence gaps.
02
A method-design brief
Assay rationale, study requirements and prospective performance criteria.
03
A technical assessment
Interpretation, limitations and practical recommendations for the next decision.
Clear scope from the outset. Genometrion provides scientific advisory and analytical method-development consulting. Laboratory testing, where required, is scoped separately with appropriately qualified providers.
Start with the question
Complex therapies.
Clearer analytical decisions.
Define the scientific question behind your project. We can discuss the evidence, methods and practical next steps.
Scientific enquiries
Let’s talk about your project.
A brief, nonconfidential outline is a useful starting point.
contact@genometrion.comEmail GenometrionOpens your email application. Contact details and enquiry guidance.